Eppendorf Launches First CO2 Incubator Shaker with Integrated 180°C Sterilization for Enhanced Contamination Control

01 October 2024 | Tuesday | News


The newly developed CellXpert® CS220 sets a new benchmark in mammalian shake flask culture by integrating advanced sterilization features, ensuring higher contamination prevention and increased productivity in cell cultivation projects.

First CO2 incubator shaker on the market with  integrated 180 °C sterilization routine 

Expression of complex recombinant proteins, the production of viral vectors  in mammalian cells, or the production of bioreactor starter cultures is  primarily done in shake flask cultures inside CO2 incubator shakers. A major  risk factor for reliable budget- and time-planning of these projects is  contamination, especially with viruses or Mycoplasma.  

“Our new CellXpert® CS220 was developed specifically to speed up  mammalian shake flask culture projects and to meet the industry’s  increasing need for higher contamination prevention standards.” says Maria  Mattern, responsible for innovations of the Eppendorf´s shaker and CO2 incubator portfolio. “ 

“Most, if not all current CO2 incubator shakers in the market are  microbiological shakers with optional CO2 control. This is also reflected in  the low level of cleanability and missing sterilization functions of these  devices, as contamination is usually not a major issue in microbiological  applications,” says Mattern.  

Produced in Hamburg, Germany, the CellXpert CS220 is the first shaker to  apply the established contamination protection standards of CO2 incubator based cell cultivation—180 °C sterilization. In addition, the device expedites  disinfection by having no drive wheel, cover sheets, cables, or heating fins  inside the stainless-steel chamber. The CellXpert CS220 also features up to  40% higher flask capacity and the highest platform size to footprint ratio in  the market.  

“We are happy to welcome the new member of our CellXpert family and to  expand our successful cell culture portfolio including CO2 incubators,  shakers, high-speed centrifuges, and bioprocess equipment.”, says Mattern

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