Duality Biologics and Adcendo Expand Collaboration to Strengthen ADC Cancer Therapy Pipeline

26 November 2024 | Tuesday | News


Adcendo Exercises Option to Leverage Duality’s DITAC Platform for Additional Antibody-Drug Conjugates
Image Source : Public Domain

Image Source : Public Domain

Duality Biologics ("Duality"), a clinical-stage biotech company focusing on the discovery and development of next generation antibody-drug conjugate therapeutics today announced the expansion of its ongoing collaboration with Adcendo ApS ("Adcendo"), a biotech company focused on the development of first-in-class antibody-drug conjugates (ADCs) for the treatment of cancers with high unmet medical need.

The expansion of the parties' strategic license agreement was comprised of Adcendo exercising its option to utilize Duality's technology platform to be used in additional assets, further strengthening Adcendo's ADC pipeline.

 

In January 2023, Adcendo announced its entry into a strategic license agreement with Duality to utilize Duality's proprietary, industry leading DITAC (Duality Immune Toxin Antibody Conjugates) linker-payload platform for its uPARAP-ADC program in mesenchymal cancers. In May 2023, Adcendo announced an MTA and Option License Agreement to nominate ADCs against two novel ADC targets. Adcendo's exercise of this option results in additional ADC product candidates moving into development.

Michael Pehl, Chief Executive Officer of Adcendo, said "Our strategic collaboration with Duality allows us to progress with our aim to develop highly differentiated novel ADCs for the treatment of hard-to-treat cancers. The expansion of our first-in-class ADC pipeline built upon Duality's unique and clinically validated DITAC platform paves our way to becoming a leader in the field of ADC cancer therapy."

John ZhuFounder&Chief Executive Officer of Duality Biologics, said "Duality is dedicated to becoming a leading global next-generation ADC company. We are very glad to apply our platform through collaboration with Adcendo on breakthrough ADC medicines. We believe combining each party's unique strengths in ADC discovery and development will accelerate the innovation on ADC drugs for patients worldwide."

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