Twist Bioscience Expands DNA Synthesis Portfolio with Launch of Longer Gene Fragments up to 5.0kb

09 August 2024 | Friday | News


CEO Emily M. Leproust highlights enhanced capabilities of Twist's Gene Fragments, offering increased length, low error rates, and rapid turnaround, empowering researchers across various applications from RNA therapeutic screening to antibody discovery.
Image Source : Public Domain

Image Source : Public Domain

-Twist Bioscience Corporation , a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today announced the expansion of its DNA synthesis offering with the launch of Gene Fragments with increased lengths ranging from 1.8kb to 5.0kb.

“Leveraging our Express Genes workflow, industry-leading error rate and rapid turnaround times, we continue to push the boundaries of what is possible in DNA synthesis to expand our portfolio of products that enable our customers to quickly and efficiently advance their research,” said Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience. “Our goal is to serve all researchers no matter where they are in their customer journey, whether they are Makers, Buyers or transitioning from Makers to Buyers. With the versatility, speed, high quality, scalability, competitive pricing, and now increased length of Twist Gene Fragments, we can further penetrate the Maker's Market and meet the needs of customers who previously had to stitch together shorter fragments, as well as enable customers working in RNA therapeutic screening applications.”

Twist’s low error rate of 1:7,500 base pairs enables the production of longer fragments that can be easily incorporated into workflows, allowing researchers to select fewer colonies for screening or to use the gene fragments directly in in vitro transcription to make RNA. The increased length of the Gene Fragment gives researchers the ability to further customize and incorporate more elements into the fragment. Turnaround time for all Gene Fragments starts at two business days, regardless of length.

Twist Gene Fragments

Twist Gene Fragments are universally compatible with various downstream cloning methods, allowing for seamless integration into a wide array of applications. They can be utilized in protein engineering, antibody discovery, pathway engineering, functional genomics, diagnostic assays and other fields. Twist Gene Fragments are customizable and have no order limit. Turnaround time for Gene Fragments 0.3-5.0kb starts at two business days.

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