BioMed X & Merck KGaA, Darmstad Launch New Research Program in Oncology

05 July 2021 | Monday | News

BioMed X, a leading independent research institute, announced today the start of its eighth joint research program with Merck KGaA, Darmstadt, Germany. The new program will explore the role of extrachromosomal DNA in cancer and it will complement the research of two ongoing oncology programs at BioMed X in the fields of DNA damage response and RNA splicing.
Image Source : Public Domain

Image Source : Public Domain


  • BioMed X Institute expands its collaboration with Merck KGaA, Darmstadt, Germany to a total of eight research programs.
  • Call for application of the new research program 'Extrachromosomal DNA in Cancer' to open now.

Extrachromosomal circular DNA (ecDNA) was recently found to be particularly abundant in multiple human cancer cells, although its frequency varies among different cancer types. Elevated levels of ecDNA have been considered to be correlated with poor clinical outcome in human cancers.

“We are pleased to extend our collaboration even further in the field of cancer research,” Christian Tidona, Founder and Managing Director of the BioMed X Institute said. “This new program will strengthen our expertise at the forefront of deep cancer biology which can potentially lead to better treatment options for patients.”

The key aim of the new project will be to generate a comprehensive atlas of extrachromosomal DNA in human cancer tissues, to investigate how (onco)genes in ecDNA could contribute to tumorigenesis, disease progression, tumor heterogeneity, metastasis, and treatment resistance and to develop novel therapeutic strategies based on oncogenic alterations in ecDNA.



Stay Connected

Sign up to our free newsletter and get the latest news sent direct to your inbox


Forgot your password?



Lost your password? Please enter your email address. You will receive a link to create a new password.

Back to log-in