07 January 2022 | Friday | News
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Under this agreement, ProBioGen develops a scalable process and granted Imvaq® a license to use ProBioGen's AGE1.CR.pIX cell line for the manufacturing of a MVA-based cancer immunotherapy candidate.
ProBioGen's duck suspension cell line AGE1.CR.pIX is designed to support industrial, GMP-compliant production of a wide variety of vaccine strains and viral vectors in different bioreactor formats in chemically-defined media. The cell line has been exhaustively tested against adventitious agents and vectors produced on AGE1.CR.pIX have been used in clinical trials.
Dr. John Choi, CEO of Imvaq said: "After an initial demonstration study, the AGE1.CR.pIX platform convinced us to engage ProBioGen for process development to initiate a rapid and scalable manufacturing process for our uniquely engineered cancer immunotherapy and to negotiate a commercial license of this outstanding platform."
Dr. Volker Sandig, Chief Scientific Officer at ProBioGen stated: "Yields and purity are important determinants for successful implementation of vaccines or virotherapeutics. The AGE1.CR.pIX cell line was shown to be highly permissive for innovatively designed vectors and we are pleased to complement Imvaq's novel cancer immunotherapy strategy with our manufacturing approach."