HistoIndex, a pioneer in AI-driven digital pathology solutions for chronic liver disease, has announced the continued expansion of its commercial partnership network in the United States with the addition of two new hepatology and gastroenterology centers - Houston Research Institute (HRI) Kingwood and Knowledge Research Center (KRC) in Orange, California.

HistoIndex is now expanding access to its integrated diagnostic services to an additional center in the HRI network (HRI Kingwood), further strengthening its growing footprint across leading hepatology and gastroenterology practices. The roll-out of HistoIndex's diagnostic services across the HRI system in late 2025 has had a positive impact on the overall workflow at HRI centers - from biopsy sample preparation, evaluation for disease status to logistical coordination with central labs.

"Over the past few months, we've seen how integrating HistoIndex's solutions across our centers has streamlined their operational workflow for processing and shipping of liver biopsies, in addition to the markedly increased consistency we've observed in the biopsy interpretations by both traditional and AI-enhanced assessments offered by HistoIndex," said Dr. Mazen Noureddin, MD, MHS, Director at Houston Research Institute and Co-Chairman of the Board at Summit and Pinnacle Clinical Research. "This translates into enhanced diagnostic confidence and better patient care outcomes, and we are glad to bring the HRI Kingwood site under the same operational sphere for the highest-quality results."

In parallel, HistoIndex has also established a new partnership with Knowledge Research Center (KRC) - a medical center in Orange, California, specializing in patient care and clinical trials across a range of therapeutic areas, including liver diseases^[1]. This partnership expands the reach of the company's unique diagnostic offering to the U.S. West Coast. "We are excited to partner with HistoIndex and integrate its AI-enhanced solutions into our clinical workflow," said Dr. Alaa Abousaif, MD, co-founder of KRC in Orange, California.

Together, the partnerships with the new hepatology and gastroenterology centers underscore HistoIndex's commitment to building a network of clinical partners and advancing objective, quantitative diagnostics in Metabolic Dysfunction-associated Steatohepatitis (MASH).