Led by Lotus Lake Capital, the financing will accelerate the development of TPM004, a differentiated ultra-long-acting amylin/calcitonin receptor dual agonist, and advance the company's proprietary PepTetris™ peptide discovery platform for obesity, diabetes, and other metabolic diseases

• Developing a differentiated portfolio of ultra-long-acting peptide therapeutics targeting metabolic diseases, including obesity, type 2 diabetes, and related disorders, with the potential to achieve best-in-class efficacy and dosing convenience
• Advancing TPM004, a next-generation ultra-long-acting amylin/calcitonin receptor dual agonist, toward IND submission and first-in-human clinical development
• Expanding the proprietary PepTetris™ peptide discovery platform, leveraging advanced peptide engineering and artificial intelligence approaches to enable the discovery of once-monthly and potentially longer-duration peptide therapeutics
• The angel financing was led by Lotus Lake Capital, with participation from Stars Capital, Tainuo Capital, Blue Ocean Capital, and renowned entrepreneur Mr. Yousheng Shen, providing strategic support to advance clinical development and platform innovation

Torrey Pines Medicine (Shenzhen) Ltd., a biotechnology company dedicated to developing next-generation ultra-long-acting peptide therapeutics for metabolic diseases,  announced the successful completion of an angel financing round raising tens of millions of RMB.

The round was led by Lotus Lake Ventures, with participation from Stars Capital, Tainuo Capital, Blue Ocean Capital, and renowned entrepreneur Mr. Yousheng Shen. The proceeds will primarily support corporate development, focus on accelerating IND filing and Phase I clinical trials for core pipeline asset TPM004, and further refine the proprietary PepTetris™ ultra-long-acting peptide technology platform to continuously empower early-stage R&D pipelines.

"We are deeply grateful for the trust and support from our investors. R&D in metabolic diseases is entering a new era. Significant unmet clinical needs remain regarding patient compliance, enhanced efficacy, and better overall therapeutic experience. At Torrey Pines Medicine, we will continue leveraging our proprietary platform to engineer globally competitive, ultra-long-acting peptide therapeutics that provide convenient and highly effective long-term management solutions for patients." said Dr. Qingsong Zhu, Co-founder and Chief Executive Officer of Torrey Pines Medicine.

Representing the lead investor in this financing, Kai Guo, partner at Lotus Lake Ventures, said, "We have long tracked global trends in metabolic innovation and firmly believe that ultra-long-acting technology represents a critical frontier for next-generation metabolic therapies. Torrey Pines Medicine combines a highly experienced international leadership team with proprietary platform technologies and a differentiated pipeline addressing significant unmet medical needs. We look forward to supporting the company as it advances its lead programs into the clinic and establishes itself as a globally recognized biotechnology company."

According to Dr. Weijun Shen, Co-founder and Chief Scientific Officer of Torrey Pines Medicine, the development of truly next-generation peptide therapeutics requires more than simply extending drug half-life. "Developing ultra-long-acting peptide medicines requires a holistic optimization of molecular design, receptor pharmacology, pharmacokinetics, manufacturability, and clinical translatability. Our objective is not simply to prolong circulation time, but to engineer molecules that deliver the optimal balance of efficacy, safety, dosing convenience, and developability."

Dr. Nieng Yan, President of the Shenzhen Medical Academy of Research and Translation (SMART) and Director of Shenzhen Bay Laboratory (SZBL), congratulated the company on completing its angel financing. "We extend our warmest congratulations to Torrey Pines Medicine on the successful completion of its angel financing. As a flagship venture incubated by Shenzhen Bay Laboratory, Torrey Pines Medicine encapsulates the deep integration of foundational research, technological innovation, and industrial translation. We look forward to seeing them leverage their international team and platform advantages to accelerate the translation of original scientific breakthroughs into clinical applications."