Delonix Bioworks, a clinical-stage biotechnology company pioneering genetically engineered bacterial vaccines, announced that the first participant has been dosed in its Phase 1 clinical trial of DX-104 in China. DX-104 is an innovative Group B meningococcal (MenB) vaccine candidate developed using the company's proprietary OMV Plus® platform. This milestone marks a significant step in the concurrent global development of DX-104, following the initiation and ongoing progress of the DX-104 First-in-Human Phase 1 trial in Australia.

The Phase 1 trial in China is a randomized, double-blind, placebo-controlled study designed to evaluate the safety and immunogenicity of DX-104 in healthy participants aged 2 to 59 years.

"The concurrent execution of Phase 1 trials in Australia and China enables the generation of clinical data across diverse populations, providing robust validation of our OMV Plus® platform's distinct advantages and global development potential," said Dr. Qiubin Lin, Founder and CEO of Delonix Bioworks. "As MenB remains a significant global health threat, DX-104 is designed to deliver a next-generation vaccine with broader protection, improved tolerability, and enhanced global accessibility.