Sanyou Biopharmaceuticals (Shanghai) Co., Ltd. (hereinafter referred to as "Sanyou Bio") and Guangdong JiAnTeBo Biotechnology Co., Ltd. (hereinafter referred to as "JiAnTeBo") have signed a strategic cooperation agreement. Under the leadership of Professor Yin Zhinan, the founder and chairman of JiAnTeBo, the company has made original pioneering discoveries of new targets for metabolic diseases such as obesity, fatty liver, diabetes, and Alzheimer's disease. At present, building on its existing drug pipeline, JiAnTeBo is focusing on the development of new pipelines of agonist antibody drugs.

The purpose of this collaboration is to fully leverage the strong strength of Sanyou Bio's antibody discovery platform, involving screening from sub-libraries of Super-trillion fully human antibody library, Phage display mouse immune antibody library, and Phage display alpaca immune antibody library. Through processes such as antibody expression, purification, identification, affinity validation, and druggability analysis, the collaboration aims to identify and obtain more than 200 specific antibody drug lead molecules. JiAnTeBo will then use its comprehensive cell activity detection system for functional testing of these lead molecules. It is expected to open up new ways for the treatment of major diseases using agonist monoclonal antibodies.

Professor Yin Zhinan, the founder of JiAnTeBo, has deeply devoted to the field of immunometabolism for 30 years and is a world-leading immunologist and an eminent translational medicine scientist. He currently serves as the Dean and doctoral advisor of the Institute of Biomedical Translational Research at Jinan University. He is also a Distinguished Professor under the "Cheung Kong Scholars Programme" of the Ministry of Education and a recipient of the National Outstanding Youth Fund. Over seven years, Professor Yin Zhinan led the scientific research team to make original discoveries of multiple new targets for treating major diseases such as obesity, insulin resistance, and Alzheimer's disease. The relevant results were published in journals such as Nature and he won China Annual Important Medical Progress Award. Professor Yin also took the lead in obtaining approval for the Guangdong Provincial Major Project of Basic and Applied Basic Research (Pilot) to explore new ways to treat fatty liver and Alzheimer's disease.

Professor Yin Zhinan mentioned, "We will always be committed to finding innovative therapies in the field of metabolic diseases such as obesity, diabetes, fatty liver, and Alzheimer's disease. By partnering with Sanyou Bio, we will leverage their expertise technology and innovation capabilities in the field of antibodies, and based on our existing protein pipeline and mRNA new drug pipeline, to accelerate the layout of our original research pipeline and promote the development of agonist antibody drugs, thus bringing more effective treatment options to patients suffering major diseases around the world."

Dr. Lang Guojun, CEO of Sanyou Bio, stated, "We are thrilled to partner on R&D with JiAnTeBo, an excellent team dedicated to pioneering innovative therapies. With Sanyou Bio's three major innovative drug R&D technology platforms: 'Super-Trillion, Integration, Intelligence', we are confident in our ability to better assist JiAnTeBo in completing the strategic layout of innovative biological drugs. The strong alliance of the two parties will definitely bring new hope to more tumor and metabolic patients."

At the signing ceremony, key representatives from both companies were present to witness this significant event, including Professor Yin Zhinan (Founder), Yang Guang (CEO), and Yang Hengwen (CTO) from JiAnTeBo and Dr. Lang Guojun (CEO), Li Shuangqi (Project Director), Ren Zhiqiang (Project Leader), and Yang Aochu (Reginal Manager of Technical Services in South China) from Sanyou Bio.