Non-profit drug developer TB Alliance has granted Remington Pharmaceutical Industries (Pvt.) Ltd. a non-royalty bearing license to market the anti-tuberculosis (TB) medicine pretomanid as part of the all-oral, six-month BPaL and BPaLM regimens for treatment of drug-resistant TB (comprised of bedaquiline, pretomanid, and linezolid, with or without moxifloxacin). Pakistan ranks third among countries designated by the World Health Organization as having a high burden of drug-resistant TB. Remington has agreed to develop, manufacture, and commercialize pretomanid in Pakistan and the collaboration may extend to other countries in the future.

"TB Alliance is proud to partner with a leading healthcare solutions company in Pakistan to help ensure this treatment is available and accessible to those who need it throughout the country," said Mel Spigelman, President and CEO of TB Alliance. "This exciting update ensures an affordable and sustainable market for state-of-the-art therapies for drug-resistant TB in Pakistan."

"Pakistan is dedicated to eliminating TB and drug-resistant TB as public health threats. We applaud Remington Pharmaceuticals and TB Alliance for partnering to bring this medication to those affected with TB, and our government will work diligently to make sure that patients throughout the country can access the BPaL and BPaLM regimens," said Dr. Abdul Baseer Khan Achakzai, Director General of Health, Ministry of National Health Services, Pakistan.

"Remington is proud and thrilled to collaborate with TB Alliance to provide solutions that could change the lives of drug-resistant TB patients in Pakistan. Being the first national pharmaceutical company to attain WHO Prequalification from Pakistan, we strive to make quality TB products accessible to all. We are committed to the fight against tuberculosis and this partnership will support our global efforts to eliminate this disease efficiently. Our established distribution pathways will help doctors reach patients throughout the country," said Dr. Abdul Qadeer Khokhar, Chairman of Remington Pharmaceuticals.

The partnership with Remington is part of TB Alliance's global commercialization strategy for pretomanid as part of the BPaL/BPaLM regimens. This agreement is meant to complement four previously announced partnerships with manufacturers who were strategically recruited to ensure adequate quantities of quality assured product globally, and to enable market competition to ensure pretomanid is affordable for all countries.