Volta Labs, a leader in automation for genomics, and New England Biolabs® (NEB®), a world-renowned provider of life science reagents,  announced a co-development partnership to expand the portfolio of NEBNext® reagents available on the Callisto™ Sample Preparation Platform.

The collaboration combines Volta's fully automated NGS sample preparation system with NEB's trusted, high-performance NEBNext NGS sample preparation kits to deliver reproducible, walk- away automation.

"Our collaboration with NEB extends Callisto's mission to make advanced sequencing more accessible and reproducible," said Udayan Umapathi, CEO of Volta Labs. "By bringing NEB's gold-standard chemistries onto the platform, we're enabling labs to run trusted WGS workflows automatically — without sacrificing flexibility or performance."

Menu expansion: NEBNext® Ultra™ II FS Library Prep for Whole-Genome Sequencing

The two companies are developing NEBNext® chemistries on the Callisto platform, starting with NEBNext® Ultra™ II FS DNA Library Prep Kit for Illumina sequencing.

This fully automated workflow integrates NEB reagents into Callisto's digital fluidics platform, enabling researchers and clinical labs to perform high-yield, high-quality library preparation with minimal hands-on time and maximum consistency.

This expansion will further enhance Callisto's "Any Sequencer, Any Chemistry" approach — allowing labs to prepare high-quality WGS libraries across multiple platforms such as Illumina, Oxford Nanopore, PacBio, and Ultima Genomics using pre-validated NEB reagents.

"We're excited to see our reagents integrated into innovative automation platforms like Callisto," said Andrew Barry, Associate Director, Portfolio Management, NGS at NEB. "By combining NEB's proven enzymology with the power of Callisto, we can deliver robust, high-fidelity NGS workflows that meet the needs of today's genomics labs."

Simplified, Consistent, and Scalable Library Preparation

The Callisto platform automates DNA extraction, fragmentation, library preparation, and enrichment within a compact, benchtop system. The integration of NEB reagents provides:

• Consistency: Highly uniform fragment sizes and cleaner libraries across every batch
  
  
• Speed: Full setup in < 30 minutes, with 3 hours of walk-away runtime
  
  
• Flexibility: Pre-validated workflows compatible with multiple sequencing systems