Ampio Pharmaceuticals (NYSE American: AMPE), a clinical stage biopharmaceutical company focused on the advancement of immunology-based therapies for prevalent inflammatory conditions, today announced that the Company is expected to join the small cap  Russell 2000^® Index and the broad-market Russell 3000^® Index at the conclusion of this year's reconstitution of the Russell stock indexes, effective after the U.S. stock market opens on Monday, June 28, 2021, accordingly to a preliminary list of additions posted on June 4, 2021.

Michael Macaluso, the Company's President and Chief Executive Officer, stated, "Inclusion in the Russell Indexes is an important milestone and will increase the overall awareness and exposure of our Company within the investment community."

Annual Russell indexes reconstitution captures the 4,000 largest U.S. stocks as of May 7, 2021, ranking them by total market capitalization. Membership in the U.S. all-cap Russell 3000 Index, which remains in place for one year, means automatic inclusion in the large-cap Russell 1000^® Index or small-cap Russell 2000^® Index as well as the appropriate growth and value style indexes. FTSE Russell determines membership for its Russell indexes primarily by objective market-capitalization rankings and style attributes.

Russell U.S. Indexes are part of the FTSE Russell, a leading global index provider, and are widely used by investment managers and institutional investors as the basis for index funds and as benchmarks for active investment strategies. FTSE Russell reports approximately $10.6 trillion in assets are benchmarked against Russell's U.S. indexes. For more information on the Russell 3000^® Index and Russell 2000^® Index and the Russell U.S. Indexes reconstitution, visit the "Russell Reconstitution" section at FTSE Russell website.