Evolve your processes with clinically proven cell therapy solutions

31 August 2022 | Wednesday | Product Spotlight


Advance your T cell research to the clinic with confidence

Cell Therapy Systems (CTS) OpTmizer T Cell Expansion Serum-Free Medium (SFM), no phenol red

CTS-Op-Tmizer

 

Gibco™ CTS™ OpTmizer™ T Cell Expansion SFM, no phenol red and the CTS™ Dynabeads™ CD3/CD28 have a proven track record of scaling up, and together they can help simplify your transition into clinical and commercial manufacturing.

 

Developed with cell performance at the forefront, this serum-free and xeno-free medium supports the growth and expansion of human T lymphocytes in multiple culture formats.

 

CTS OpTmizer T Cell Expansion SFM, no phenol red:

  • Supports high-density T cell culture (>4 x 106 CD3 T cells/mL), including CAR T cells
  • Supports T cell activation using Gibco™ Dynabeads™ products, stimulatory or artificial antibody-presenting cells, and soluble antibody protocols
  • Supports phenotype, functions (e.g., cytokine secretion profile), and viability similar to T cells cultured in conventional medium supplemented with FBS or human AB serum

 

 

Discover how the CTS OpTmizer T Cell Expansion SFM, no phenol red can enhance your cell growth »

 

 

CTS Dynabeads™ CD3/CD28

 

Dynabeads

 

CTS Dynabeads CD3/CD28 simultaneously isolates and activates T cells based on CD3 and CD28 co-expression and allows you to achieve desired naive and early memory phenotypes. T cells are isolated with high recovery (>90%) and purity (>95%) with uniform stimulation (>95% CD25+ at day 3 post-activation). Activated and expanded T cells preserve a young phenotype (CD28+ CD62L+) with low PD-1 expression at days 7–10, as well as a demonstrated increase in clonal diversity compared to starting T cells.

 

Explore the benefits of CTS Dynabeads CD3/CD28 in your T cell clinical and commercial manufacturing »

 

Speak to a bioprocessing representative about our new T cell expansion serum-free media and Dynabeads CD3/CD28 offering »

 

 

 

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