Kevin Green, Chief Operating Officer of Elsie Biotechnologies, expressed enthusiasm, stating, "We are pleased that GSK has elected to license our platform technology following the research collaboration. GSK is a great innovator in the field of oligonucleotide therapeutics, and this license validates the potential of our discovery platform, which we believe can power next-generation RNA medicines, optimized for safety, activity, and delivery."
Christine Donahue, VP of Molecular Modalities Discovery at GSK, echoed the sentiment, emphasizing, “We are excited to continue our work with Elsie which aligns so closely with our focus at the intersection of science and tech. It builds on our industry-leading position in advanced platform technologies and exemplifies our commitment to the potential of oligonucleotide therapeutics.”
Elsie’s discovery platform stands out as an unparalleled ultra-high throughput proprietary process enabling comprehensive evaluation of oligonucleotide chemical space. Through the application of proprietary encoding technology, Elsie evaluates all potential sequences or chemical modification patterns, aiming to enhance activity, reduce toxicity, and improve delivery of oligonucleotide therapeutic candidates. Additionally, Elsie employs proprietary P(V) chemistry technologies, including a suite of novel reagents and processes, to synthesize diverse oligonucleotide therapeutics with precise synthetic control.
Per the agreement terms, Elsie will receive a license payment from GSK, alongside potential development and commercial milestones on a target-by-target basis. This collaboration underscores a shared commitment to pushing the boundaries of innovation in oligonucleotide therapeutics, promising novel solutions for patients worldwide.