"BSI-045B is a next generation anti-TSLP mAb with high affinity and bioactivity that has the potential to offer greater therapeutic potential for patients with AD" said Dr. Hugh Davis, Chief Operating Officer of Biosion, Inc. and President of Biosion USA. "Initiating the phase II clinical trial is an important step toward our goal of developing antibody-based therapeutics for patients with unmet medical needs worldwide"

The phase I study of BSI-045B demonstrated its potential to be a first-in-class treatment for AD due to its single dose activity in a cohort of AD patients, excellent PK and favorable safety profile. The phase II study is designed to assess the efficacy of BSI-045B as monotherapy as well as in combination therapy with Dupixent^® to further increase therapeutic effectiveness for patients who are suffering from AD.

In addition to this study, Biosion's collaboration partner - CTTQ, a China-based pharmaceutical company with rights to BSI-045B (TQC2731) for China development and commercialization, is currently conducting a Phase II clinical trial of BSI-045B in China for the treatment of severe uncontrolled asthma.