• The Riverview facility provides comprehensive services for active pharmaceutical ingredients (APIs) and high potency APIs (HPAPIs), including specialized solutions for payload-linkers.
• This cutting-edge suite will significantly enhance the company's ability to support global payload-linker development and manufacturing and help partners bring complex therapies like antibody-drug conjugates (ADCs) and other bioconjugates to market.

Piramal Pharma Solutions, a leading global Contract Development and Manufacturing Organization (CDMO) and part of Piramal Pharma Ltd. (NSE: PPLPHARMA) (BSE: 543635) ("PPS"), has officially unveiled a new, state-of-the-art payload-linker development and manufacturing suite at its Riverview, Michigan drug substance facility. This launch is a key element of the company's broader $90 million investment plan to extend U.S.-based manufacturing capabilities, announced last year. In addition to the payload-linker suite, the plan will add new technology and enhanced commercial-scale manufacturing capabilities at PPS's dedicated sterile injectables facility in Lexington, Kentucky. These strategic enhancements reinforce PPS's commitment to bringing complex and innovative therapies to patients quickly and reliably.

"The launch of our new payload-linker suite at Riverview marks a major milestone for PPS and our partners," said Peter DeYoung, CEO, Piramal Global Pharma. "The suite places world-class expertise, advanced technology, and commercial-scale payload-linker capabilities right here in Michigan, empowering our customers to accelerate the development and delivery of life-changing therapies, like ADCs. This investment demonstrates our deep commitment to U.S.-based innovation and manufacturing, ensuring our partners benefit from unmatched efficiency, supply chain security, and a seamless path from concept to clinic for these critical medicines."

With over 60 years of drug substance development and manufacturing experience, Riverview is a distinguished leader in its field. Drawing on its diverse expertise, the site provides a comprehensive range of capabilities for APIs and HPAPIs. Leveraging its specialized HPAPI knowledge and abilities, Riverview serves as PPS's dedicated payload-linker supplier, making it critical to ADCelerate™ – PPS's rapid, integrated approach to phase I ADC development.

The addition of this payload-linker suite is designed to help PPS accelerate partners' timelines and adapt to evolving market needs. Equipped with advanced containment, automation, and analytical technologies, the suite enables seamless scaling of payload-linker programs. This further strengthens the ADCelerate™ platform and positions PPS to meet the rising demand for ADCs and other bioconjugate therapies.

The expansions in Riverview and Lexington reinforce PPS's position as the partner of choice for innovator companies looking for patient-centric, U.S.-based drug development and manufacturing solutions.