Sanofi K.K. (Head office: Shinjuku-ku, Tokyo; President: Takahiko Iwaya; hereinafter "Sanofi") and Health2Sync. (Head office: Taito-ku, Tokyo; CEO: Ed Deng) have entered into a partnering agreement to support healthcare professionals and people living with diabetes mellitus through digital support programs.

Health2Sync, a digital health startup, specializing in diabetes and other chronic disease management, has developed a healthcare/lifestyle app that has been used by about 290,000 users in Japan. Recently the mean HbA1c level has tended to increase among people living with diabetes mellitus.^[i] Patients are receiving an average of 14.8 units of baseline insulin and have an HbA1c of 7.8%, which indicates that the basal insulin dose may be further optimized if an appropriate approach is taken.^[ii] 

It is not easy for people living with diabetes to continue recording their blood glucose levels to achieve their treatment goals. One of the challenges is that the environment to help them sufficiently control the disease is not fully fostered. Through this partnering agreement, Sanofi and Health2Sync will work together to develop digitized features for healthcare providers and patients on insulin in Japan that will help improve Hypoglycemia/Hyperglycemia insulin management by connected caps for insulin, and titration alerts, to people living with diabetes.

The two companies initiated their collaboration in Taiwan in September 2020 by providing digital health solutions to HCPs and patients and have witnessed a good adoption within more than 200 clinics and more than 10,000 insulin patients having already joined the program as of May 2022.

On this initial traction, Sanofi and Health2Sync announced last year that they will further develop an automated digital insulin management solution with titration algorithms to further enhance the efficiency of insulin treatment. The two companies are collaborating to generate studies on the therapeutic effects of the digital solution.

This agreement in Japan again emphasizes the companies' ambition to realize a more comprehensive chronic disease management through digital solutions. 

Moving forward, Sanofi and Health2Sync plan to further collaborate in bringing innovative digital therapeutics solutions to patients and healthcare professionals in Japan and other markets.